Complexity and algorithms for copy-number evolution problems
نویسندگان
چکیده
منابع مشابه
Copy-Number Evolution Problems: Complexity and Algorithms
Cancer is an evolutionary process characterized by the accumulation of somatic mutations in a population of cells that form a tumor. One frequent type of mutations are copy number aberrations, which alter the number of copies of genomic regions. The number of copies of each position along a chromosome constitutes the chromosome’s copy-number profile. Understanding how such profiles evolve in ca...
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ژورنال
عنوان ژورنال: Algorithms for Molecular Biology
سال: 2017
ISSN: 1748-7188
DOI: 10.1186/s13015-017-0103-2